Lopez-Persem – JNeurosci – The human ventromedial prefrontal cortex: sulcal morphology and its influence on functional organization

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Verhagen, Gallea – eLife – Offline impact of transcranial focused ultrasound on cortical activation in primates

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Folloni, Verhagen – Neuron – Manipulation of subcortical and deep cortical activity in the primate brain using transcranial focused ultrasound stimulation

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Vijayakumar – BrainStrucFunc – Mapping multiple principles of parietal-frontal cortical organization using functional connectivity

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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neural circuits

“The brain is not porridge” <Dick Passingham>   The brain is highly differentiated and structured. Not one bit is like any other. At the same time, no bit acts alone: each region is highly integrated and connected with other areas. In fact, the contribution of a brain region to cognition and behaviour is shaped by […]

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Eichert – Cortex – What is special about the human arcuate fasciculus? Lateralization, projections, and expansion

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Mars – eLife – Whole brain comparative anatomy using connectivity blueprints

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Mars – CurrOpBehavSci – Connectivity and the search for specializations in the language-capable brain

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Meder – NatComm – Simultaneous representation of a spectrum of dynamically changing value estimates during decision making

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Zimmermann – BrainStrucFunc – Is the extra striate body area part of the dorsal visuomotor stream?

Referential pointing is a characteristically human behavior, which involves moving a nger through space to direct an addressee towards a desired mental state. Planning this type of action requires an interface between sensorimotor and conceptual abilities. A simple interface could supplement spatially-guided motor routines with communicative-ostensive cues. For instance, a pointing nger held still for […]

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Mars – NeurosciBioRev – Comparing brains by matching connectivity profiles

The great promise of comparative neuroscience is to understand why brains differ by investigating the relations between variations in the organization of different brains, their evolutionary history, and their current ecological niche. For this approach to be successful, the organization of different brains needs to be quantifiable. Here, we present an approach to formally comparing […]

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Mars – BrainStrucFunc – The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study

We compared the course and cortical projec- tions of white matter fibers passing through the extreme capsule in humans and macaques. Previous comparisons of this tract have suggested a uniquely human posterior pro- jection, but these studies have always employed different techniques in the different species. Here we used the same technique, diffusion MRI, in […]

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Johnen – eLife – Causal manipulation of functional connectivity in a specific neural pathway during behaviour and at rest

Correlations in brain activity between two areas (functional connectivity) have been shown to relate to their underlying structural connections. We examine the possibility that functional connectivity also reflects short-term changes in synaptic efficacy. We demonstrate that paired transcranial magnetic stimulation (TMS) near ventral premotor cortex (PMv) and primary motor cortex (M1) with a short 8-ms […]

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Mars – FrontNeurosci – Primate comparative neuroscience using magnetic resonance imaging: promises and challenges

Primate comparative anatomy is an established field that has made rich and substantial contributions to neuroscience. However, the labor-intensive techniques employed mean that most comparisons are often based on a small number of species, which limits the conclusions that can be drawn. In this review we explore how new developments in magnetic resonance imaging have […]

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Volman – JNeurosci – Reduced serotonin transporter availability decreases prefrontal control of the amygdala

After a threatening event, the risk of developing social psychopathologies is increased in short-allele (s) carriers of the serotonin trans- porter gene. The amygdala becomes overresponsive to emotional stimuli, an effect that could be driven by local hypersensitivity or by reduced prefrontal regulation. This study distinguishes between these two hypotheses by using dynamic causal modeling […]

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Volman – CerebCortex – Endogenous testosterone modulates prefrontal–amygdala connectivity during social emotional behavior

It is clear that the steroid hormone testosterone plays an important role in the regulation of social emotional behavior, but it remains unknown which neural circuits mediate these hormonal influences in humans. We investigated the modulatory effects of endogenous testosterone on the control of social emotional behavior by applying functional magnetic resonance imaging while healthy […]

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Grol – JNeurosci – Parieto-frontal connectivity during visually guided grasping

Grasping an object requires processing visuospatial information about the extrinsic features (spatial location) and intrinsic features (size, shape, orientation) of the object. Accordingly, manual prehension has been subdivided into a reach component, guiding the hand toward the object on the basis of its extrinsic features, and a grasp component, preshaping the fingers around the center […]

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